Product Name :
NSUN2 Recombinant Rabbit Monoclonal Antibody [PSH05-05]
Predicted band size :
87 kDa
Observed band size :
100 kDa
Synonyms:
5 methycytoisine methyltransferase antibody D13Wsu123e antibody FLJ20303 antibody hTrm4 antibody MISU antibody Myc induced SUN domain containing protein antibody NOL1/NOP2/Sun domain family 2 antibody NOL1/NOP2/Sun domain family 2 protein antibody NOL1/NOP2/Sun domain family member 2 antibody NSUN 2 antibody 展开
Function :
NOP2/Sun domain family, member 2 is a protein that in humans is encoded by the NSUN2 gene. Alternatively spliced transcript variants encoding different isoforms have been noted for the gene. The protein is a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA (Leu)(CAA) precursors.(R)-VANOL In stock This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. NSUN2 is also localized on mitochondria and is capable of introducing post-transcriptional modifications in mitochondrial tRNAs. Mutations in this gene have been found associated to cases of Dubowitz-like syndrome.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Recombinant protein within human NSUN2 aa1-767.4-Bromo-1-(3-fluorophenyl)-1H-pyrazole uses
Species reactivity:
Human, Mouse, Monkey
Verify application:
WB, IF-Cell, IHC-P, IF-Tissue, IP
Coupling :
unconjugated
Clone number:
PSH05-05
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.PMID:33375865 Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 87 kDa
Positive control :
HeLa cell lysate, HepG2 cell lysate, Jurkat cell lysate, HEK-293 cell lysate, 293T cell lysate, A431 cell lysate, HCT 116 cell lysate, Caco-2 cell lysate, Neuro-2a cell lysate, COS-1 cell lysate, human testis tissue, human small intestine tissue, HeLa.