Product Name :
Nox1 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
GP91 2 antibody Mitogenic oxidase (pyridine nucleotide dependent superoxide generating) antibody Mitogenic oxidase 1 antibody MOX-1 antibody MOX1 antibody NADH/NADPH mitogenic oxidase subunit P65 MOX antibody NADH/NADPH mitogenic oxidase subunit P65-MOX antibody NADPH oxidase 1 antibody NADPH oxidase 1 variant NOH 1L antibody NADPH oxidase homolog 1 antibody 展开
Function :
NADPH oxidase 1 is an enzyme that in humans is encoded by the NOX1 gene. NOH-1S is a voltage-gated proton channel that mediates the H currents of resting phagocytes and other tissues. It participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Two transcript variants encoding different isoforms have been found for this gene.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from human Nox1 425-515/515
Species reactivity:
Human, Mouse, Rat, Dog, Cow, Horse, Rabbit
Verify application:
WB, ELISA, IHC-P, IF
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year.tert-Butyl 3-(methylamino)propanoate Chemical name Avoid repeated freeze/thaw cycles.312624-65-0 site The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃.PMID:33736742 When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage buffer solution:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
62 KDa
Positive control :
NOH-1L is detected in colon, uterus, prostate, and colon carcinoma, but not in peripheral blood leukocytes. NOH-1S is detected only in colon and colon carcinoma cells.